Post by aurore on Aug 23, 2015 7:05:07 GMT
AMISULPRIDE
a) is the medication a typical / atypical antipsychotic?
Atypical antipsychotic
b) common brand names
Amisulpride Sandoz®
Amisulpride Winthrop®
APO-Amisulpride
Sulprix
Amipride®
Solian®
c) normal dose range
400 to 800mg PO daily for acute psychotic episodes, increased up to 1200mg PO daily if required
d) common side effects
CNS: dystonia, extrapyramidal reactions, insomnia, nervousness, oculogyric crisis, tardive dyskinesia, hyperactive behaviour, seizure, neuroleptic malignant syndrome
CV: bradycardia, hypertension, orthostatic hypotension, prolonged QT interval, venous thromboembolism,
Endocrine: galactorrhoea, hypothyroidism, hyperglycaemia, weight gain,
GI: constipation, dyspepsia, hypersalivation
GU: amenorrhoea, impotence
Hepatic: raised liver enzymes
Metabolic: hyperglycaemic, weight increase
Musculoskeletal: dystonia
Psychiatric: agitation, anxiety, depression
Skin: pruritis
Other:allergic reactions, breast pain, gynaecomastia
e) contraindications
*individuals hypersensitive to the drug or any of the ingredients
*breastfeeding or planning to breastfeed
*taking the following medications
- medicines used to treat irregular heart rhythm such as quinidine,
disopyramide, amiodarone and sotalol
- cisapride
- antibiotics such as erythromycin and pentamidine, given as an
injection into the veins
- levodopa, a medicine used in Parkinson's disease
- thioridazone, an antipsychotic
- methadone, medicine used to treat pain or addiction
*the packaging is torn or shows signs of tampering or the tablets do not look quite right
*the expiry date o the pack has passed
*individuals with the following medical conditions
-phaeochromocytoma, a rare tumour of the adrenal glands which sit near the kidneys
-tumour of the pituitary gland, a small gland at the base of the brain
-breast cancer
-liver disease
*in children to the age of 18years
f) special monitoring / nursing care requirements
*closely monitor mental status and blood pressure
* use cautiously in individuals with prolonged QT interval, CV disease, cerebrovascular disease, dehydration, hypovolaemia, history seizures, exposure to extreme heat or conditions that could affect metabolism or haemodynamic responses
*monitor blood glucose levels closely in individuals with history of diabetes mellitus
*monitor for tardive dyskinesia, which may occur after prolonged use
*Alert: Watch for neuroleptic malignant syndrome (extrapyramidal effects, hyperthermia, autonomic disturbance). It is rare but usually fatal. it is not necessarily related to length of drug use or type of neuroleptic; elevated levels of creatinine, phosphokinase are associated with neuroleptic malignant syndrome.
*Drug may increase serum prolactin level
g) education requirements for patients / families / carers
*Inform the patient/family/carer what to tell the doctor before the patient starts the medication:
1. any allergic reaction to any medicine which you have taken previously to treat your current condition.
2. you are pregnant or intend to become pregnant. Amisulpride Sandoz is not recommended for use in pregnancy. If you need to take Amisulpride Sandoz
during pregnancy you should discuss the benefits and risks of taking it with your doctor.
3. you suffer from lactose intolerance because Amisulpride Sandoz tablets contain lactose.
4. you have kidney or liver disease, Parkinson's disease orfits (seizures).
5. you have problems with the heart and blood vessels.
6. you have, or have a history of blood clots.
7. you have hyperglycaemia (high sugar levels in the blood) or a family history of diabetes. Your doctor may recommend monitoring your blood sugar levels while you are taking Amisulpride Sandoz.
8. you suffer from dementia.
9. you have any mental/mood changes or suicidal thoughts. Patients (and caregivers of patients) need to monitor for any worsening of their
condition and/or the development of thoughts of suicide, suicidal behaviour or
thoughts of harming themselves. Seek medical advice immediately if these symptoms present.
10. you have risk factors for stroke
11. taking other medications , including any that you buy without a prescription from your pharmacy, supermarket or health food store
12. if you are unsure about any medicine you are taking, you should check with your doctor or pharmacist. They will have more information on medicines to be
careful of while you are taking Amisulpride Sandoz
*Administration of medication:
-How much to take
-How to take it - Tablets, Oral solution
-When to take it - Amisulpride Sandoz tablets should preferably be taken before meals. Take your prescribed dose at about the same time each day.
-How long to take it- It is important that you do NOT stop taking Amisulpride Sandoz unless your doctor tells you. Do not stop taking your Amisulpride Sandoz just because you feel better. It is very important to continue Amisulpride Sandoz
because it will help you stay well.
-If you forget to take it - take your dose as soon as you remember, do not take a double dose to make up for the dose that you missed
-If you take to much - Immediately telephone your doctoror the Poisons Information Centre (telephone Australia 13 11 26 or New Zealand 0800 POISON or
0800 764766), or go to Accident and Emergency at your nearest hospital, if you think that you or anyone else may have taken too much Amisulpride Sandoz. Show the doctor your pack of tablets. Do this even if there are no signs of discomfort or poisoning. If you have taken too much Amisulpride Sandoz, the most common signs are drowsiness and slurred speech
*Things the patient must do:
-Tell all doctors, dentists and pharmacists who are treating you that you are taking Amisulpride Sandoz.
-While you are taking AmisulprideSandoz, tell your doctor or pharmacist before you start any new medicine.
-Tell your doctor immediately, or go to the nearest hospital, if you have suicidal thoughts or mental/mood changes
-Occasionally, the symptoms of depression may include thoughts of suicide or self-harm. These symptoms may continue to get worse during the early stages of
treatment until the effect of the medicine becomes apparent. All mentions of suicide or violence must be taken seriously
*Things to be careful:
- Be careful driving or operating machinery until you know how Amisulpride Sandoz affects you
-Be careful if you are elderly or unwell. Some people may experience side effects such as drowsiness, confusion, dizziness and unsteadiness, which may increase the risk of a fall
-The effects of alcohol could be made worse while taking Amisulpride Sandoz. It is NOT recommended that you drinkalcohol while taking Amisulpride Sandoz
-Be careful while taking antihistamines, sleeping tablets or tablets to relieve pain while taking this medicine. Amisulpride Sandoz can increase drowsiness caused by
medicines affecting your nervous system
-Do not give Amisulpride Sandoz to anyone else
*Side Effects:
-Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Amisulpride Sandoz
-Tell your doctor if you notice any of the following and they worry you:
drowsiness, weight gain, dizziness, increased appetite, constipation, dry mouth, insomnia, anxiety, agitation
-Also go to the Accident and Emergency at your nearest hospital if you notice any of the following:
muscle twitching, abnormal movements mainly in the face or tongue, fever, faster breathing, sweating, muscle stiffness
-After prolonged use in women, medicines of this type can cause:
breast pain, milk secretion, an absence of their monthly period, changes in the regularity of their periods
-Tell your doctor if your monthly periods are absent for six months or more.
-After prolonged use in men, medicines of this type can cause breast enlargement or impotence
- Incidences of abnormal liver function have been occasionally reported
-Tell your doctor if you notice any symptoms that worry you
*Storage:
-Keep your tablets in the blister pack until it is time to take them
-Keep Amisulpride Sandoz tablets in a cool, dry place where the temperature stays below 30°C
-Do not store Amisulpride Sandoz or any other medicine in the bathroom or near a sink
-Do not leave it in the car or on window sills
-Heat and dampness can destroy some medicines
-Keep it where children cannot reach it.
-There will be an expiry daten(month, year) on your Amisulpride Sandoz container. The medicine should not be taken after this date.
*Disposal:
- If your doctor tells you to stop taking Amisulpride Sandoz or the tablets have passed their expiry date, ask your pharmacist what to do with the amount left over.
*Product Description
*Product Ingredients
*Contact Numbers and websites for further information and Emergencies
REFERENCES
Better Health Channel. Amisulpride Sandoz. Retrieved from www.health translations.vic.gov.au/bhcv2/bhcmed.nsf/cmipages/CMI8361
McKenna, L., & Mirkov, S. (2012). Australia New Zealand nursing and midwifery drug handbook (6th ed.). NSW: Lippincott Williams & Wilkins Pty Ltd
a) is the medication a typical / atypical antipsychotic?
Atypical antipsychotic
b) common brand names
Amisulpride Sandoz®
Amisulpride Winthrop®
APO-Amisulpride
Sulprix
Amipride®
Solian®
c) normal dose range
400 to 800mg PO daily for acute psychotic episodes, increased up to 1200mg PO daily if required
d) common side effects
CNS: dystonia, extrapyramidal reactions, insomnia, nervousness, oculogyric crisis, tardive dyskinesia, hyperactive behaviour, seizure, neuroleptic malignant syndrome
CV: bradycardia, hypertension, orthostatic hypotension, prolonged QT interval, venous thromboembolism,
Endocrine: galactorrhoea, hypothyroidism, hyperglycaemia, weight gain,
GI: constipation, dyspepsia, hypersalivation
GU: amenorrhoea, impotence
Hepatic: raised liver enzymes
Metabolic: hyperglycaemic, weight increase
Musculoskeletal: dystonia
Psychiatric: agitation, anxiety, depression
Skin: pruritis
Other:allergic reactions, breast pain, gynaecomastia
e) contraindications
*individuals hypersensitive to the drug or any of the ingredients
*breastfeeding or planning to breastfeed
*taking the following medications
- medicines used to treat irregular heart rhythm such as quinidine,
disopyramide, amiodarone and sotalol
- cisapride
- antibiotics such as erythromycin and pentamidine, given as an
injection into the veins
- levodopa, a medicine used in Parkinson's disease
- thioridazone, an antipsychotic
- methadone, medicine used to treat pain or addiction
*the packaging is torn or shows signs of tampering or the tablets do not look quite right
*the expiry date o the pack has passed
*individuals with the following medical conditions
-phaeochromocytoma, a rare tumour of the adrenal glands which sit near the kidneys
-tumour of the pituitary gland, a small gland at the base of the brain
-breast cancer
-liver disease
*in children to the age of 18years
f) special monitoring / nursing care requirements
*closely monitor mental status and blood pressure
* use cautiously in individuals with prolonged QT interval, CV disease, cerebrovascular disease, dehydration, hypovolaemia, history seizures, exposure to extreme heat or conditions that could affect metabolism or haemodynamic responses
*monitor blood glucose levels closely in individuals with history of diabetes mellitus
*monitor for tardive dyskinesia, which may occur after prolonged use
*Alert: Watch for neuroleptic malignant syndrome (extrapyramidal effects, hyperthermia, autonomic disturbance). It is rare but usually fatal. it is not necessarily related to length of drug use or type of neuroleptic; elevated levels of creatinine, phosphokinase are associated with neuroleptic malignant syndrome.
*Drug may increase serum prolactin level
g) education requirements for patients / families / carers
*Inform the patient/family/carer what to tell the doctor before the patient starts the medication:
1. any allergic reaction to any medicine which you have taken previously to treat your current condition.
2. you are pregnant or intend to become pregnant. Amisulpride Sandoz is not recommended for use in pregnancy. If you need to take Amisulpride Sandoz
during pregnancy you should discuss the benefits and risks of taking it with your doctor.
3. you suffer from lactose intolerance because Amisulpride Sandoz tablets contain lactose.
4. you have kidney or liver disease, Parkinson's disease orfits (seizures).
5. you have problems with the heart and blood vessels.
6. you have, or have a history of blood clots.
7. you have hyperglycaemia (high sugar levels in the blood) or a family history of diabetes. Your doctor may recommend monitoring your blood sugar levels while you are taking Amisulpride Sandoz.
8. you suffer from dementia.
9. you have any mental/mood changes or suicidal thoughts. Patients (and caregivers of patients) need to monitor for any worsening of their
condition and/or the development of thoughts of suicide, suicidal behaviour or
thoughts of harming themselves. Seek medical advice immediately if these symptoms present.
10. you have risk factors for stroke
11. taking other medications , including any that you buy without a prescription from your pharmacy, supermarket or health food store
12. if you are unsure about any medicine you are taking, you should check with your doctor or pharmacist. They will have more information on medicines to be
careful of while you are taking Amisulpride Sandoz
*Administration of medication:
-How much to take
-How to take it - Tablets, Oral solution
-When to take it - Amisulpride Sandoz tablets should preferably be taken before meals. Take your prescribed dose at about the same time each day.
-How long to take it- It is important that you do NOT stop taking Amisulpride Sandoz unless your doctor tells you. Do not stop taking your Amisulpride Sandoz just because you feel better. It is very important to continue Amisulpride Sandoz
because it will help you stay well.
-If you forget to take it - take your dose as soon as you remember, do not take a double dose to make up for the dose that you missed
-If you take to much - Immediately telephone your doctoror the Poisons Information Centre (telephone Australia 13 11 26 or New Zealand 0800 POISON or
0800 764766), or go to Accident and Emergency at your nearest hospital, if you think that you or anyone else may have taken too much Amisulpride Sandoz. Show the doctor your pack of tablets. Do this even if there are no signs of discomfort or poisoning. If you have taken too much Amisulpride Sandoz, the most common signs are drowsiness and slurred speech
*Things the patient must do:
-Tell all doctors, dentists and pharmacists who are treating you that you are taking Amisulpride Sandoz.
-While you are taking AmisulprideSandoz, tell your doctor or pharmacist before you start any new medicine.
-Tell your doctor immediately, or go to the nearest hospital, if you have suicidal thoughts or mental/mood changes
-Occasionally, the symptoms of depression may include thoughts of suicide or self-harm. These symptoms may continue to get worse during the early stages of
treatment until the effect of the medicine becomes apparent. All mentions of suicide or violence must be taken seriously
*Things to be careful:
- Be careful driving or operating machinery until you know how Amisulpride Sandoz affects you
-Be careful if you are elderly or unwell. Some people may experience side effects such as drowsiness, confusion, dizziness and unsteadiness, which may increase the risk of a fall
-The effects of alcohol could be made worse while taking Amisulpride Sandoz. It is NOT recommended that you drinkalcohol while taking Amisulpride Sandoz
-Be careful while taking antihistamines, sleeping tablets or tablets to relieve pain while taking this medicine. Amisulpride Sandoz can increase drowsiness caused by
medicines affecting your nervous system
-Do not give Amisulpride Sandoz to anyone else
*Side Effects:
-Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Amisulpride Sandoz
-Tell your doctor if you notice any of the following and they worry you:
drowsiness, weight gain, dizziness, increased appetite, constipation, dry mouth, insomnia, anxiety, agitation
-Also go to the Accident and Emergency at your nearest hospital if you notice any of the following:
muscle twitching, abnormal movements mainly in the face or tongue, fever, faster breathing, sweating, muscle stiffness
-After prolonged use in women, medicines of this type can cause:
breast pain, milk secretion, an absence of their monthly period, changes in the regularity of their periods
-Tell your doctor if your monthly periods are absent for six months or more.
-After prolonged use in men, medicines of this type can cause breast enlargement or impotence
- Incidences of abnormal liver function have been occasionally reported
-Tell your doctor if you notice any symptoms that worry you
*Storage:
-Keep your tablets in the blister pack until it is time to take them
-Keep Amisulpride Sandoz tablets in a cool, dry place where the temperature stays below 30°C
-Do not store Amisulpride Sandoz or any other medicine in the bathroom or near a sink
-Do not leave it in the car or on window sills
-Heat and dampness can destroy some medicines
-Keep it where children cannot reach it.
-There will be an expiry daten(month, year) on your Amisulpride Sandoz container. The medicine should not be taken after this date.
*Disposal:
- If your doctor tells you to stop taking Amisulpride Sandoz or the tablets have passed their expiry date, ask your pharmacist what to do with the amount left over.
*Product Description
*Product Ingredients
*Contact Numbers and websites for further information and Emergencies
REFERENCES
Better Health Channel. Amisulpride Sandoz. Retrieved from www.health translations.vic.gov.au/bhcv2/bhcmed.nsf/cmipages/CMI8361
McKenna, L., & Mirkov, S. (2012). Australia New Zealand nursing and midwifery drug handbook (6th ed.). NSW: Lippincott Williams & Wilkins Pty Ltd